Research
The main focus of my lab is to engineer novel methodologies for the automatization and enhancement of clinical procedures in the field of neuromodulation for neurological disorders such as Parkinson’s Disease, essential tremor, and epilepsy. To achieve this, my lab focuses on exploring and identifying neurological markers that reflect the patient pathophysiological status.
Our Research Framework
Towards that goal, the experimental approaches used in my laboratory to study cortical, basal ganglia, and thalamic circuits in humans include:
1) intraoperative local field potential and single-cell recordings during routine DBS implantation surgeries, together with electromyography and inertial sensors;
2) local field potentials recorded from chronic DBS implants, such as Medtronic Percept;
3) non-invasive electroencephalogram under different medication and stimulation conditions;
4) advanced imaging and modeling techniques (as part of Lead-DBS team).
Objective mapping and outcome prediction for DBS
Patient specific models of pathologically induced changes in network activity
Novel paradigms for adaptive neuromodulation therapies
Advances in imaging techniques
and sharing with the community through open source efforts
